Results of the joint transnational call JTC 2022

14 consortia were selected for financing for a total amount of 15.1 million euros.

Results of the joint transnational call JTC 2022
Results of the joint transnational call JTC 2022

15.1 million euros have been awarded to 14 excellent projects under the call JTC 2022 on “Novel translational approaches to tackle the challenges of hard-to-treat cancers from early diagnosis to therapy”.

The awarded projects are listed below in alphabetical order according to their acronym.

Project Acronym 

Project Title

ANGELAEarly detection of esophageal squamous cell carcinoma with the Cytosponge coupled with molecular biomarkers and machine learning
BileCanMetPrecision medicine in cholangiocarcinoma: accurate tools for early detection and identification of PRMT5 as a novel pharmacological target
CAR4PDACHijacking stroma antigens for CAR-T cell immunotherapy of PDAC
iCC-StratRisk stratification and subtyping of intrahepatic cholangiocarcinoma for early detection of recurrence and response to immuno-therapy
IdeaTMEHCCIdentification of therapeutic targets using HCC DErived organoid Augmented with TME components.
MATTO-GBMMultimodality Artificial intelligence open-source Tools for Radiation Treatment Optimization in patients with Glioblastoma
NK-4-GBMMetabolically optimised NK cell therapies for Glioblastoma
PaCaNanoDevelopment of a pancreatic cancer drug-nanocarrier system selectively targeting tumour cells and tumour stroma to overcome treatment failure
PANC-P53Innovative peptide- and RNA-based strategies to modulate p53 for pancreatic cancer therapy
PLASTIGTackling tumor heterogeneity and PLASTIcity as resistance mechanisms in Glioblastoma
PRECEDENCEGenotype matched therapies in intrahepatic cholangiocarcinoma: a multi-pronged strategy for improving efficacy and combating resistance.
ReachGLIOReaching the heterogeneous vascular landscape of glioblastoma with multifunctional nanomedicines.
SIMMBAPSystemic immunological determinants of tumor evolution and therapy response in BRCA-mutated pancreatic cancer
T-Plex EACT-Plex-Capture: Isolation of neoantigen-specific CD8+ T cell receptors for patient-specific immunotherapy in esophageal adenocarcinoma (EAC)